A clinical trial comparing two different methods of rectal cancer surgery.

COMPARISON OF CIRCUMFERENTIAL RESECTION MARGIN IN STANDARD VS EXTRALEVATOR ABDOMINOPERINEAL EXCISION: A RANDOMISED CONTROLLED TRIAL - CRAPE STUDY

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2013/05/003649

Enrollment

Registered

2013-05-20

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- carcinoma rectum. Patients diagnosed with Carcinoma Rectum will be studied in this trial

Interventions

Intervention1: Extralevator Abdominoperineal excision (APE): the patient is turned to prone position for perineal dissection after completing the abdominal part of dissection. Control Intervention1: S

Eligibility

Inclusion criteria

Inclusion criteria: 1. All patients diagnosed with low rectal adenocarcinoma (within 5cm from anal verge), admitted under Department of General Surgery Unit 2 2. Planned for abdominoperineal excision with curative intent.

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

Measure	Time frame
Rates of positive circumferential margin between the two operative techniques.Timepoint: less than 2mm	—

Secondary

Measure	Time frame
1. Intra-operative bowel(rectal) perforation rates 2. Intra-operative injury to adjacent structures. 3. Total operative time 4. Duration of hospital stay Timepoint: intra-operative and post-operative till discharge	—

Countries

India

Contacts

Public ContactDr Amrit Pipara

Christian Medical College

markranjan@hotmail.com9486843884

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026