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Comparison of inhalation techniques in children with asthma using metered dose inhaler and spacer

A randomised controlled trial to compare the effectiveness of single maximal inhalation with breath holding versus five tidal breaths for inhalation of salbutamol delivered by metered dose inhaler and spacer in children with asthma.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2013/04/003559
Enrollment
60
Registered
2013-04-15
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Bronchial asthma

Interventions

Intervention1: MDI 2puffs (100mcg, in each puff): MDI two puff either by five tidal breathing method or single maximal inhalation with a breath hold method ( for each puff) Control Intervention1: Sing

Sponsors

Divya Anna Stephen
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Children with asthma a) Using metered dose inhaler. b) Who are of age 5-15 yrs. c) Whose parentâ??s give consent to participate in the study. 2. Children who are able to perform the manoeuvre for measuring PEFR. 3. Children who are able to perform breath holding.

Exclusion criteria

Exclusion criteria: 1. Children with a) Acute exacerbations of asthma. b) Chest malformation, congenital abnormalities of the chest. c) Any other cardiovascular or neuromuscular disease. d) Anthropometric parameters less than 3rd percentile. 2. Children receiving regular long acting beta-2 agonist (salmetrol, formetrol). 3. Children who have received beta2 agonist, 6 hrs prior to the observation (salbutamol). 4. Children who have received methylxanthines and anti cholinergic drugs prior to observation (Ipratropium bromide,Theophylline). 5. Children who are already performing single maximal inhalation with a breath hold

Design outcomes

Primary

MeasureTime frame
Peak expiratory flow rateTimepoint: O1-Immediately prior to intervention. O2-Half an after intervention.

Secondary

MeasureTime frame
Breath hold time duration in single maximal inhalation with a breath hold groupTimepoint: Not applicable

Countries

India

Contacts

Public ContactDr S K Kabra

All India Institute Of Medical Sciences

mvatsa2001@yahoo.co.in01126594457

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 4, 2026