Comparison of two different locations in the heart for placing a pacemaker wire

Comparison of long term clinical outcomes of right ventricular apical pacing and right ventricular outflow tract pacing

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2013/04/003543

Enrollment

Registered

2013-04-10

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- High grade permanent AV block needing pacemaker implantation

Interventions

Intervention1: Right Ventricular Outflow tract pacing: Transvenous placement of an active fixation lead in the septal RVOT for permanent pacing Control Intervention1: Right ventricular apical pacing:

Eligibility

Inclusion criteria

Inclusion criteria: Patients needing permanent pacemaker implantation with a ventricular lead for permanent AV block

Exclusion criteria

Exclusion criteria: Atrial fibrillation, LVEF < 45%, Known critical stenoses of main coronary arteries, Inability to follow up, Exercise limitation due to pathological process of other systems, significant valvular heart disease, Percutaneous or surgical revascularisation within the last 3 months, Life expectancy of < 2 years

Design outcomes

Primary

Measure	Time frame
1) Difference in LV ejection fraction at 2 years. 2) Difference in 6 minute walk test Timepoint: 1 year and 2 years	—

Secondary

Measure	Time frame
Difference in QRS widthTimepoint: immediate post procedure, 1 year and 2 years	—

Countries

India

Contacts

Public ContactRaja J Selvaraj

Jawaharlal Institute of Postgraduate Medical Education and Research

rajajs@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026