None listed
Conditions
Interventions
Intervention1: Taurine: Single dose(0.4% taurine present in Red bull)
One group- taurine ,other group- placebo(water)- given once
Sleep deprivation- two days
Control Intervention1: Water: one group- t
Sponsors
Vir Chandra Singh Garhwali Government Medical Science and research institute
Eligibility
Inclusion criteria
Inclusion criteria: Normal healthy volunteers with no physical or laboratory abnormalities.
Exclusion criteria
Exclusion criteria: 1) Significant uncontrolled systemic illness, i.e. diabetes, congestive heart failure, renal or hepatic disease. 2) History of consumption of anti inflammatory drugs for four weeks before starting the trial. 3) History of consumption of CNS affecting drugs for four weeks before starting the trial. 4) History of antioxidants or cognition enhancing substances for four weeks before starting the trial. 5) History of smoking and alcohol consumption for last four weeks. 6) Any intake of caffeinated drinks 48 hours prior to study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To investigate the role of taurine in modulating the state of inflammation produced due to acute sleep deprivation (acute stressor) in human participants. Timepoint: 25days | — |
Secondary
| Measure | Time frame |
|---|---|
| To follow the effects of taurine in regulation of acute stress induced inflammation in relation to its impact on cognitive performance. To explore the action of taurine on glucose metabolism in acute stress. To report any unprecedented side effects which surface during the trial due to administration of taurine. Timepoint: three weeks | — |
Countries
India
Contacts
Public ContactPriyanka Singh
Vir Chandra Singh Garhwali Govt Institute of Medical Science and Research, Srikot
Outcome results
None listed