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Oral fluids through jejunal tube versus intravenous fluids in acute pancreatitis

Comparison of Intravenous Fluids with Early Administration of Nasojejunal Feeds: A Randomized Trial assessing the Feasibility & Impact on the Course, Complications and Outcome of Acute Severe Pancreatitis.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2013/03/003494
Enrollment
100
Registered
2013-03-18
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Acute Severe Pancreatitis

Interventions

Intervention1: Nasojejunal fluids: 4.5 L of Nasojejunal fluids through nasojejunal route for 48 hours Control Intervention1: Intravenous fluids: 4.5 L of intravenous fluids per day for 48 hours

Sponsors

Prof DK Bhasin
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All acute severe pancreatitis on admission

Exclusion criteria

Exclusion criteria: 1. Patients who are already on or fit to be on oral diet 2. Patients who have mild disease. 3. Critically ill patients who cannot undergo endoscopic guided tube placement.

Design outcomes

Primary

MeasureTime frame
1. Safety and tolerability of nasojejunal feeds. 2. Development of pancreatic necrosis and infection (pancreatic or extrapancreatic). 3. Reduction in the serum TNF-alfa, IL-1 and IL-6 levels. Timepoint: Periodically during the hospital stay and at time of discharge/death—

Secondary

MeasureTime frame
1. Mortality, morbidity and length of hospital stay. 2. Need for and time to interventions (endoscopic, percutaneous, surgery). Timepoint: During hospital stay—

Countries

India

Contacts

Public ContactProf DK Bhasin

Department of Gastroenterology

deepakkbhasin@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026