A clinical trial to study the effect of two dosage forms of a herb(Leonotis nepetifolia)in patients with Osteoarthritis

A randomized parallel group clinical trial to compare the efficacy of extract capsule and decoction of Leonotis nepetifolia(L.) R.Br in patients with Osteoarthritis.

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2013/03/003465

Enrollment

Registered

2013-03-08

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Osteoarthritis

Interventions

Intervention1: Leonotis nepetifolia decoction and Leonotis nepetifolia water extract: The two dosage forms of the trial drug will be compared to evaluate the efficacy between the two Intervention2: Le

Eligibility

Inclusion criteria

Inclusion criteria: Patients with symptoms of sandhivata

Exclusion criteria

Exclusion criteria: Other types of sandhi vyadhis like ama vata, vata rakta and koshtrukasirsha Uncontrolled systemic diseases like Hypertension, diabetes mellitus and kidney disease.

Design outcomes

Primary

Measure	Time frame
Baseline evaluation will be done based on the symptoms of Sandhivata- sandhi shula, sandhi shotha,akunchana prasarana vedana, sandhigraha, sandhisputana, sparshasahatva. Scoring pattern will be 0-no symptom, 1-mild symptom,2 moderate symptom,3-severe The evaluation will be repeated at week 3 and week 6(end point)Timepoint: Baseline Week 3 End point at week 6	—

Secondary

Measure	Time frame
Visual Analog scale for Pain and WOMAC Qestionnaire will be done at Baseline and End pointTimepoint: Baseline and End point	—

Countries

India

Contacts

Public ContactReshmi Pushpan

IPGTand RA

nishteswar@yahoo.co.in08141521049

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026