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To compare the effects of two drugs dexmedetomidine and fentanyl when used in spinal anaesthesia.

Comparative study on the spinal block characteristics of intrathecal dexmedetomidine and fentanyl as adjuvants to bupivacaine.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2013/03/003451
Enrollment
60
Registered
2013-03-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- comparing the effect of adding 2 drugs - dexmedetomidine and fentanyl on duration of spinal anaesthesia

Interventions

Intervention1: dexmedetomidine: 5 microgram to be given intrathecally Control Intervention1: fentanyl: 25 microgram to be given intrathecally

Sponsors

Nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 & 11 patients undergoing lower abdominal and genitourethral surgeries

Exclusion criteria

Exclusion criteria: Hypertension, cardiac diseases including conduction defects, contraindications to spinal anaesthesia, allergy to amide type of local anaesthetics or dexmedetomidine or fentanyl

Design outcomes

Primary

MeasureTime frame
difference between the duration of sensory blockade when dexmedetomidine and fentanyl are used as adjuvants to bupivacaine in spinal anaesthesiaTimepoint: 5, 10, 15, 20, 25, 30, 45, 60, 75, 90, 105, 120, 135, 150, 165, 180, 195, 210, 225, 240.—

Secondary

MeasureTime frame
to compare motor block characteristics, sedation score and side effect profile of the two drugs in study.Timepoint: 5, 10, 15, 20, 25, 30, 45, 60, 75, 90, 105, 120, 135, 150, 165, 180, 195, 210, 225, 240—

Countries

India

Contacts

Public ContactDR BINCY V THOMAS

Government Medical College, Thiruvananthapuram

linettemorris5@gmail.com09447772436

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026