A clinical trial to study the effect of etodolac alone in comparison with combination of etodolac and eperisone in patients of osteoarthritis of knee joint.

A pragmatic study of etodolac in comparison with combination of etodolac and eperisone hydrochloride- An open trial in patients of osteoarthritis of knee joint.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2013/03/003442

Enrollment

Registered

2013-03-01

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Osteoarthritis knee

Interventions

Intervention1: etodolac: etodolac 600mg OD orally for 8 weeks Control Intervention1: combination of etodolac and eperisone hcl: etodolac 600mg OD and eperisone hcl 50mg tds orally for 8 weeks

Eligibility

Inclusion criteria

Inclusion criteria: Confirmed cases of Osteoarthritis knee on X-ray

Exclusion criteria

Exclusion criteria: Patients having other forms of inflammatory arthritis, patients with active peptic ulcer, significant renal, hepatic, hematological or cardiovascular disease and patients with hypersensitivity to NSAIDs, patients with h/o of skin disorders aggravated by drugs, patients of myasthenia gravis, pregnant women and nursing mothers

Design outcomes

Primary

Measure	Time frame
Pain intensity on Visual analog scaleTimepoint: At baseline, at 4 weeks and at 8 weeks	—

Secondary

Measure	Time frame
Joint tenderness,swelling,erythema,pain on movement,functional capacity and overall arthritic condition on Likert five point scaleTimepoint: baseline, 4 weeks and 8 weeks	—

Countries

India

Contacts

Public ContactNavjot kaur

Government Medical College and Rajindra Hospital, Patiala

harinder390@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 10, 2026