To compare the effectiveness of antioxidants versus no treatment for male partner for improving pregnancy rates in couples undergoing In vitro fertilization (IVF) for abnormal semen analysis.

Pre treatment with antioxidants versus no treatment for male partner in couples undergoing assisted reproductive technology (ART) for male infertility: a randomized controlled trial.

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2013/02/003431

Enrollment

200

Registered

2013-02-26

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Men with abnormal semen parameters for which the couples are undergoing ART in view of male factor infertility

Interventions

Intervention1: Vitamin C, Vitamin E, Zinc: Tablet Vitamin C 500 mg, Capsule Vitamin E 400 mg and Tablet Zinc 140 mg OD for 3 months Control Intervention1: No treatment: No treatment

Eligibility

Inclusion criteria

Inclusion criteria: Couples undergoing ART due to male factor infertility with the following parameters Mild Oligozoospermia 1-15 million/ml AND/OR Asthenozoospermia AND/OR Teratozoospermia <4 % normal morphology

Exclusion criteria

Exclusion criteria: Severe oligozoospermia Taken treatment in past 3 months for male infertility Female age > 37 years Female partner - moderate or severe endometriosis

Design outcomes

Primary

Measure	Time frame
Clinical pregnancy rateTimepoint: February 2015	—

Secondary

Measure	Time frame
Ongoing pregnancy rate Miscarriage rate Fertilisation rate Live birth rate Changes in sperm parametersTimepoint: February 2015	—

Countries

India

Contacts

Public ContactMohan S Kamath

Christian Medical College and Hospital

dockamz@gmail.com04162283301

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 19, 2026