A clinical trial to study the effect of two local anaesthetic drug, proparacaine and lignocaine in children undergoing elective strabismus surgery.

Comparison of topical lignocaine gel 2% and proparacaine 0.5% eye drops for perioperative analgesia and prevention of oculocardiac reflex in children undergoing elective strabismus surgery

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2013/02/003425

Enrollment

120

Registered

2013-02-22

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Strabismus

Interventions

Intervention1: lignocaine: 2% lignocanie gel, once Control Intervention1: proparacaine: one drop of proparacaine as required

Eligibility

Inclusion criteria

Inclusion criteria: All children aged 1-14 years undergoing elective strabismus surgery

Exclusion criteria

Exclusion criteria: Refusal to participate by parents ii. Difficult airway iii. Mental retardation iv. Severe cardiac/ respiratory disease

Design outcomes

Primary

Measure	Time frame
as an adjunct to intravenous analgesiaTimepoint: start of surgery till 24 hours after surgery	—

Secondary

Measure	Time frame
1.prevention of intraoperative oculocardiac reflex 2.Prevention of postoperative nausea and vomiting 3.Reduction in postoperative painTimepoint: 1. during surgery 2.24 hours postoperatively	—

Countries

India

Contacts

Public ContactRenu Sinha

AIIMS, New Delhi

renuagarwal4@rediffmail.com011-26252858

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026