Health Condition 1: null- thrombocytopenia
Conditions
Interventions
Intervention1: Platelet mass based transfusion as compared to transfusion based on platelet count: randomised controlled study of platelet mass based versus platelet count based transfusion in thrombo
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: Newborn babies upto the age of 44 weeks postmenstrual age, i.e. 4 weeks after expected date of delivery with severe thrombocytopenia admitted in the NICU, Sir Ganga Ram Hospital, New Delhi.
Exclusion criteria
Exclusion criteria: 1.Newborn with Major/life-threatening congenital malformations 2.Known immune thrombocytopenia 3.Birth weight less than 1000 g or less than 30 weeks gestational age and 1st week of life
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of platelet transfusions in two group of subjects who receive transfusions based on either platelet count or platelet massTimepoint: end of trombocytopenic episodes i.e. once the platelet count is more than 1.0 lac on two consecutive occasions. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Correlation of MPV and platelet count. 2.Incidence of major and severe haemorrhage in both groups of platelet transfusions. 3.Mortality in two groups. Timepoint: 1. For each platelet count and MPV during the study period. 2. and 3.At the time of end of thrombocytopenia episode | — |
Countries
India
Contacts
Public ContactAJIT KUMAR
SIR GANGA RAM HOSPITAL
Outcome results
None listed