Health Condition 1: null- Children with very severe pneumonia
Conditions
Interventions
Intervention1: Isotonic Fluid: 0.9 % saline as parenteral maintenance fluid according to Holliday Segar formula up till a period of 24 hours.
Control Intervention1: Hypotonic Fluid: 0.18 % as parenter
Sponsors
Lady Hardinge Medical College
Eligibility
Inclusion criteria
Inclusion criteria: Fever with cough with fast breathing and chest indrawing with nasal flaring or grunting plus at least one of the following Central cyanosis Inability to breastfeed or drink or vomiting everything Convulsions lethargy or Unconsciousness Severe respiratory distress
Exclusion criteria
Exclusion criteria: Meningitis Encephalitis Congestive cardiac failure Known Renal disease Chronic Liver Disease Shock at presentation Severe acute malnutrition Known endocrinal disease Refusal of consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients developing hyponatremia that is serum sodium less than 135 mmol per litre after receiving intravenous maintenance fluids.Timepoint: At 6 hours At 12 hours At 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of patients developing clinically symptomatic hyponatremia Timepoint: At 6 hours At 12 hours At 24 hours;Proportions of patients developing hypernatremia that is serum sodium more than 150 mmol per litreTimepoint: At 6 hours At 12 hours At 24 hours | — |
Countries
India
Contacts
Public ContactDr Praveen Kumar
Department of Pediatrics Lady Hardinge Medical College
Outcome results
None listed