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Clinical and genetic study of defective gonadal development or function due to inadequate secretion of pituitary gonadotropins

Genotype-Phenotype and Radiological Correlation of Idiopathic Hypogonadotropic Hypogonadism

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2013/02/003381
Enrollment
200
Registered
2013-02-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Idiopathic Hypogonadotropic Hypogonadism

Interventions

None listed

Sponsors

Diamond Jubilee Society Trust
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Subjects presenting with poor secondary sexual characteristics with a) Low Testosterone /Low Estradiol b) Low or inappropriately normal FSH, c) Low or inappropriately normal LH

Exclusion criteria

Exclusion criteria: Patient with HH due to 1. Tumors 2. Infiltrative/Inflammatory disorders 3. Trauma 4. Radiation 5. Post surgery 6. Functional gonadotropin deficiency 7. Combined pituitary hormone deficiency

Design outcomes

Primary

MeasureTime frame
Help in understanding the genetic basis of the disorder in Indian patients with IHH. Genetic counseling of the first degree relativesTimepoint: 5 years—

Secondary

MeasureTime frame
The information so obtained will be used to construct a practical and cost-effective flow-chart for genetic testing and counseling in Indian patients.Timepoint: 5 years—

Countries

India

Contacts

Public ContactDr Nalini S Shah

Seth G.S.Medical College and K.E.M.Hospital

nairsandhya21@gmail.com02224162917

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026