Role of antioxidants in newborns failing to initiate breathing at birth

Study effect of vitamin C, vitamin E and coenzyme Q in full term newborn with birth asphyxia.

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2013/02/003379

Enrollment

Registered

2013-02-12

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Birth asphyxia

Interventions

Intervention1: Ascorbic acid(vitamin C) and Tocopherol (vitamin E): 250 mg of vitamin C( 2 doses given at an interval of 24 hours, in pulverised oral form via infant feeding tube) and 200 IU of vitami

Eligibility

Inclusion criteria

Inclusion criteria: 1.Newborns with Apgar score of 2.Clinical features suggestive of neonatal encephalopathy (coma, seizures or hypotonia).

Exclusion criteria

Exclusion criteria: 1. Newborn hospitalized in NICU after 6 hrs of birth 2. Gestational age 3. Lethal congenital anomaly

Design outcomes

Primary

Measure	Time frame
Severity of birth asphyxia, mortality and neurodevelopmental outcomeTimepoint: Neurodevelopmental outcome at 6 months of age	—

Secondary

Measure	Time frame
Duration of hospitalisation and mechanical ventilation.Timepoint: At time of discharge or expiry.	—

Countries

India

Contacts

Public ContactJayendra R Gohil

Government Medical College, Bhavnagar

jayukids@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026