Health Condition 1: R730- Abnormal glucose
Conditions
Interventions
Intervention1: Fenugreek: 10-15 gm/day/orally for 3 years
Intervention2: Yoga: 40minutes/day for total duration of 3 Years
Control Intervention1: Placebo: Rava/suji powder 10-15 gm/day/orally for 3 Ye
Sponsors
Research Society for Study of Diabetes in India RSSDI
Lokumal Kishinchand Charity Trust
Eligibility
Inclusion criteria
Inclusion criteria: 1.male and female aged 30-70 years 2.body mass index = > 23 kg/m2 3.Fasting plasma glucose 100-125 mg/dl (IFG) 4.Post 75 g oral glucose load plasma glucose (OGTT) 140-199 mg/dl (IGT) 5.willing to sign informed consent form
Exclusion criteria
Exclusion criteria: 1.Those taking drugs known to alter glucose tolerance 2.Type1 diabetes mellitus 3.Fasting triglycerides 400 mg/dl 4.History of cancer, any major illness of the liver, kidney and central nervous system 5.Significant cardiovascular disease defined as Decompensated heart failure (NYHA class III and IV) Diagnosis of unstable angina pectoris Recent (within the last 6 months) myocardial infarction 6.Female who are pregnant, breast feeding or planning a pregnancy during the course of the study. 7.Subjects on systemic glucocorticoids, beta blockers, thiazides and nicotinic acid 8. Known hypersensitivity to the drug
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine whether Yoga and fenugreek can prevent the composite outcome of type 2DM in non diabetic people with IGT/IFG.Timepoint: yearly | — |
Secondary
| Measure | Time frame |
|---|---|
| Do these interventions convert IGT/IFG to NGT and lower FPG/PPPG and HbA1c in non diabetic people with IGT/IFG?Timepoint: Yearly;Do these interventions improve B-cell function/reduce various indices of insulin resistance (i.e.fasting hyper insulinemia, HOMA -IR) in people who are at high risk for type 2DM?Timepoint: Yearly;Do these interventions improve dyslipidemia?Timepoint: Yearly;Do these interventions improve hypertension?Timepoint: Yearly;Do these interventions improve Quality of Life?Timepoint: Yearly;Do these interventions reduce weight, W/H ratio and BMI?Timepoint: Yealy | — |
Countries
India
Contacts
Public ContactDr S V Madhu
UCMS, Delhi
Outcome results
None listed