Health Condition 1: null- Vitiligo
Conditions
Interventions
None listed
Sponsors
Employees State Insurance Corporation Post Graduate Institute of Medical Sciences Research
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with vitiligo attending dermatology outpatient clinic 2. Age group 18-45 years (at the time of entry into study) 3. Constant dietary habits for the past 1 year
Exclusion criteria
Exclusion criteria: 1. Cigarette smoking 2. Alcohol intake during past 3 months 3. Intake of folic acid, vitamin B6 and B12 during past 2 months 4. Intake of antioxidant supplements during past 3 months 5. Any systemic disease associated with altered serum Hcy levels. This will include known cases of cardiovascular disease, renal failure, diabetes mellitus, hypertension, hypothyroidism, hyperthyroidism & chronic liver disease and patients with any relevant findings on general and systemic examination. 6. Dermatological diseases known to affect serum Hcy levels, including psoriasis, Behcetâ??s disease, SLE. 7. Intake of any drugs known to affect Hcy levels, including methotrexate, INH, isotretinoin, cyclosporine, penicillamine, phenytoin, carbamazepine, OCPs, hydralazine, L-dopa, procarbazine, acetylcysteine, cholestyramine and cycloserine. 8. Pregnant females and females in 1-week postpartum period 9. Patients with any haematological or biochemical abnormality observed during routine laboratory investigations
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare levels of serum homocysteine and total antioxidant status of cases to those of controlsTimepoint: 10 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To correlate levels of serum homocysteine and serum antioxidant status in vitiligo patients with the activity of the diseaseTimepoint: 10 months | — |
Countries
India
Contacts
Public ContactDR PASCHAL DSOUZA
Employees State Insurance Corporation - Post Graduate Institute of Medical Sciences & Research
Outcome results
None listed