comparison of levetiracetam with phenobarbitone in neonatal seizure

comparison of levetiracetam with phenobarbitone for the treatment of seizure in term and near term neonates.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2013/01/003310

Enrollment

Registered

2013-01-21

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- all neonates with convulsion of any cause

Interventions

Intervention1: levetiracetam: levetiracetam to be loaded @ 60mg/kg/dose to be diluted in normal saline given over 5-10 minutes Control Intervention1: phenobarbitone: At 1st episode of convulsion phen

Eligibility

Inclusion criteria

Inclusion criteria: all newborns <28 days with convulsions of any cause.

Exclusion criteria

Exclusion criteria: babies on mechanical ventilation and with refractory shock

Design outcomes

Primary

Measure	Time frame
control of clinical seizureTimepoint: 24 hrs	—

Secondary

Measure	Time frame
side effects of levetiracetam nuerological outcome at age 3,6,12 monthsTimepoint: 12 months	—

Countries

India

Contacts

Public ContactDr Monica roy

LLRM MEDICAL COLLEGE

ANUAMIT7@REDIFFMAIL.COM0937405009

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026