A clinical trial to compare the effect of clonidine administration by two different routes, intravenous and surgical site infiltration,on pain after gall bladder surgery

Comparison of postoperative analgesic effect of clonidine through intravenous administration versus wound infiltration in patients undergoing open cholecystectomy

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2012/12/003258

Enrollment

Registered

2012-12-26

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Post surgical pain

Interventions

Intervention1: 1.Intravenous clonidine OR 2.Clonidine subcutaneous inflitration.: 1. 3 mcg/kg intravenous clonidine diluted in 1 ml normal saline after gall bladder removal 2. 3 mcg/kg subcutaneous c

Eligibility

Inclusion criteria

Inclusion criteria: Patients posted for elective open cholecystectomy under general anesthesia

Exclusion criteria

Exclusion criteria: Patients with ASA physical status 3 or 4, Patients with morbid obesity, patients receiving adrenoceptor agonist, antagonist or narcotics

Design outcomes

Primary

Measure	Time frame
Postoperative pain and analgesic requirementTimepoint: 24 postoperative hours	—

Secondary

Measure	Time frame
Side effects, like sedation, nausea-vomiting, hypotension and bradycardia Patients satisfaction scoreTimepoint: 24 postoperative hours	—

Countries

India

Contacts

Public ContactNeerja Bharti

PGIMER, Chandigarh

sujanad7@gmail.com9915575145

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 23, 2026