comparison of different anticonvulsants in neonatal seizures

STUDY OF CLINICO ETIOLOGICAL PROFILE OF NEONATAL SEIZURE AND TO COMPARE THE EFFICACY OF PHENOBARBITONE PHENYTOIN AND LORAZEPAM FOR THE TREATMENT OF NEONATAL SEIZURES

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2012/12/003255

Enrollment

105

Registered

2012-12-24

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- neonatal seizure

Interventions

Intervention1: lorazepam: 0.05mg/kg iv over 2 min single dose Control Intervention1: phenobarbital: 20mg/kg iv slowly over 20 min single dose Control Intervention2: phenytoin: 20mg/kg iv slowly over 2

Eligibility

Inclusion criteria

Inclusion criteria: neonatal seizure

Exclusion criteria

Exclusion criteria: ventilatory support hypoglycemia hypocalvemia hypo/hypernatremia

Design outcomes

Primary

Measure	Time frame
seizure subsideTimepoint: 15 minute	—

Secondary

Measure	Time frame
seizure recurrenceTimepoint: 24 hours	—

Countries

India

Contacts

Public Contactdr jayendra gohil

government medical college bhavnagar

drdhavalsolanki@gmail.com9979087670

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 5, 2026