Health Condition 1: null- 1) Prediabetes: Impaired fasting glucose(IFG) 100-125 mg/dl. 2)Age â?¥ 25 3)Serum 25(OH)D less than 30 ng/ml 4)Able and willing to provide written informed consent
Conditions
Interventions
Intervention1: vitamin D3
: Oral vitamin D3 60000IU weekly for 3 months
Control Intervention1: Placebo: oral Placebo weekly for 3 months
Sponsors
Dr Ahmed Munibuddin Government Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1) Prediabetes: Impaired fasting glucose (IFG) 100-125 mg/dl. 2)Age >= 25 3)Serum 25(OH)D less than 30 ng/ml 4)Able and willing to provide informed consent
Exclusion criteria
Exclusion criteria: 1)Diagnosed cases of diabetes or who are taking any oral glucose-lowering medication or insulin. 2)Taking vitamin D or calcium supplement. 3)Significant cardiac respiratory hepatic, renal, malignant or intestinal disease. 4)Any medication within the last month that could influence insulin secretion, insulin sensitivity, vitamin D or calcium metabolism (e.g. theophylline, phenytoin, β -blockers, diuretics, statins or reninâ??angiotensin system inhibitors, etc.);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oral Glucose Insulin sensitivity (OGIS)IndexTimepoint: 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| HOMA-IR QUICKI HbA1c BMI Serum 25 (OH) D Plasma Glucose serum insulin Timepoint: 3 months | — |
Countries
India
Contacts
Public ContactDr Urjita Sudhish Zingade
BJ Medical College, Pune
Outcome results
None listed