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Comparison of ropivacaine (a local anaesthetic) and ropivacaine with fentanyl (an analgesic) injected adjacent to thoracic vertebra to provide pain relief in patients with multiple rib fractures

Continuous paravertebral infusion of ropivacaine with or without fentanyl for pain relief in unilateral multiple fractured ribs - a prospective randomized double blind evaluation

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2012/12/003187
Enrollment
30
Registered
2012-12-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Unilateral multiple rib fractures

Interventions

Intervention1: Paravertebral ropivacaine with fentanyl: A bolus dose of ropivacaine 0.5% 0.3 ml/kg bolus followed by continuous infusion of ropivacaine 0.2% + adrenaline 5 µg/ml + fentanyl 2 µg/ml a

Sponsors

University College of Medical Sciences and Guru Teg Bahadur Hospital
Lead Sponsor
Dr AK Sethi
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients having three or more unilateral fractured ribs

Exclusion criteria

Exclusion criteria: • Unconscious patients • Patients with unstable cardiac status or severely altered mental status • Known liver/kidney disease • Known allergy to local anaesthetic drugs • Infection at site of needle insertion • Pre-existing spinal deformity • Patients having significant trauma outside chest wall, e.g. acute spine or pelvic fracture, severe traumatic brain or spinal cord injury or abdominal visceral injuries

Design outcomes

Primary

MeasureTime frame
Rescue analgesic (morphine) requirementTimepoint: Throughout study period till VAS score at rest and on coughing was not more than 10 to 15 mm for more than 8 hours

Secondary

MeasureTime frame
â?¢ VAS pain scores at rest and on coughing â?¢ Respiratory rate â?¢ Peak expiratory flow rate â?¢ Arterial oxygen saturation (SpO2) â?¢ PaO2/FiO2 ratio Timepoint: Before administration of block, 30 min after block, every 6 hours on 1st day and then every 8 hours 2nd day onwards

Countries

India

Contacts

Public ContactDr Medha Mohta

University College of Medical Sciences and Guru Teg Bahadur Hospital

eophrii@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026