Antibiotic loaded ceramic nanobeads for bone infection

Use of nano-bead hydroxyapatite implants in infected open fractures, failed implant surgeries and osteomyelitis for defect management and local delivery of appropriate antibiotics.

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2012/12/003179

Enrollment

Registered

2012-12-04

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Osteomyelitis and infected fractures and non-unions

Interventions

Intervention1: Antibiotic loaded bioceramic nanobeads: The method consists of routine assessment of a child with osteomyelitis with or without fracture. The antibiotic sensitivity will be obtained. Pa

Eligibility

Inclusion criteria

Inclusion criteria: Children with pyogenic bone infections and infected non-unions

Exclusion criteria

Exclusion criteria: Children who cannot be followed up for one year on a regular basis

Design outcomes

Primary

Measure	Time frame
Major adverse effect such as ? Allergic reactions Timepoint: Major adverse effect such as ? Allergic reactions	—

Secondary

Measure	Time frame
Eradication of infection and improvement in bone healing Timepoint: upto 2 years	—

Countries

India

Contacts

Public ContactDr Vrisha Madhuri

CHRISTIAN MEDICAL COLLEGE, VELLORE

madhuriwalter@cmcvellore.ac.in0416-2284388

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026