Comparison of the efficacy of two regimens of Vitamin D supplementation in preventing vitamin D deficiency among preterm infants.

: A Randomized double blind controlled trial comparing two regimens of Vitamin D supplementation in preterm neonates - BOND

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2012/11/003154

Enrollment

180

Registered

2012-11-29

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Vitamin D deficiency in preterm neonates.

Interventions

Intervention1: 1000 IU/ day Cholecalciferol orally : Cholecalciferol drops 1000 IU/day orally till term corrected gestational age Control Intervention1: 400 IU/day Cholecalciferol orally: Cholecalcif

Eligibility

Inclusion criteria

Inclusion criteria: All inborn preterm babies, born between 27 to 34 weeks of gestational age.

Exclusion criteria

Exclusion criteria: 1.Lack of consent 2.Neonates with major congenital anomalies 3. Maternal condition or medications likely to influence vitamin D or calcium metabolism- eg CRF, chronic liver disease, malabsorption, parathyroid disorders

Design outcomes

Primary

Measure	Time frame
Serum Vitamin D levels - Number of babies in each group that have vitamin D levels less than 20 ng/ml at 40 weeks corrected gestational age.Timepoint: 40 weeks corrected gestational age.	—

Secondary

Measure	Time frame
Serum Calcium, phosphorus, alkaline phosphatase and PTH levels at 40 weeks corrected ageTimepoint: 40 weeks corrected gestational age	—

Countries

India

Contacts

Public ContactDr Niranjan Thomas

Christian Medical College, Vellore

niranjan@cmcvellore.ac.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026