Antibiotics loaded beads for treatment of bone infection

Use of nano-bead hydroxyapatite implants in infected open fractures, failed implant surgeries and osteomyelitis for defect management and local delivery of appropriate antibiotics

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2012/11/003143

Enrollment

Registered

2012-11-23

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Osteomyelitis and infected fractures and non-unions

Interventions

Intervention1: Insertion of hydroxyapaptite nanobeads in osteomyelitic bone defect loaded with antibiotics according to: In this study,highly porous hydroxyapatite (HAP) pellets,produced by a spray dr

Eligibility

Inclusion criteria

Inclusion criteria: Children with pyogenic bone infections and infected non-unions

Exclusion criteria

Exclusion criteria: Those who cannot be followed up for one year on a regular basis

Design outcomes

Primary

Measure	Time frame
Major adverse effect such as allergic reactionsTimepoint: one year	—

Secondary

Measure	Time frame
eradication of infection and improvement in bone healingTimepoint: one year	—

Countries

India

Contacts

Public ContactDr Vrisha Madhuri

Christian Medical College, Vellore

madhuriwalter@cmcvellore.ac.in04162282171

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026