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propylthiouracil in treatment of psoriasis

Elucidation of Mechanism by which Propylthiouracil Clears Lesions in Psoriatic Patients

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2012/11/003111
Enrollment
50
Registered
2012-11-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- psoriasis

Interventions

Intervention1: Tab Propylthiouracil : Trade Name: ptu 100mg Three times a day(every 8 hours) for 12 weeks oral administration Control Intervention1: nil: nil

Sponsors

SRM UIVERSITY
Lead Sponsor
Science and Engineering Research Board Department of Science and Technology
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients with Psoriasis more than 20% of the body surface area 2.Patients who have not taken any other medication for one month prior to the study.

Exclusion criteria

Exclusion criteria: Psoriatic patients with the following criteria was excluded from the study • Pregnancy & lactation • Children below 18 yrs • Unstable psoriasis • Thyroid disorders • Other severe systemic illnesses.

Design outcomes

Primary

MeasureTime frame
Significant Decrease in Psoriasis Area and Severity Index score at 12 weeks of intervention Timepoint: 1 year 6 months

Secondary

MeasureTime frame
Determination of mechanism of action and to assess duration of remission after intervention periodTimepoint: 1 year

Countries

India

Contacts

Public ContactM Hemamalini Mphil

SRM Medical college Hospital and Research Centre, SRM University, Kattankulathur.

pushpagnanaraj@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026