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A study to measure the zinc level in blood of children with severe pneumonia and to find out the effect of zinc supplementation ( given for 14 days ) in those children on recurrence or further attacks of pneumonia in the next 3 months.

Blood Zinc Level in children with severe Pneumonia and effect of Zinc supplementation

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2012/11/003105
Enrollment
560
Registered
2012-11-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Pneumonia

Interventions

Intervention1: Zinc: 1.Dose of Zinc : 2 mo to 6 mo : 2.5 ml(10 mg) OD for 14 days 6 mo to 5 years : 5 ml(20 mg) OD for 14 days 2.2.Amoxycillin + clavulinic acid ( dose calculated on the basis of 30-5

Sponsors

Dr Aditi Baruah
Lead Sponsor
Dr Abhijit Dutta
Collaborator
Dr Meghali Chaliha
Collaborator
Mr Hiranya Saikia
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: children aged 2 â?? 60 months with severe pneumonia [who satisfy the World Health Organization (WHO) case definition of severe pneumonia ie Fever, Cough, Fast breathing (>= 50 / min in 2 mo â?? 12 mo and >= 40 / min in 1 â?? 5 yrs) and chest indrawing , requiring admission

Exclusion criteria

Exclusion criteria: 1) Very severe pneumonia as per WHO case definition 2)Severe acute malnutrition 3)Child with Tuberculosis (of any system) 4)Known case of congenital heart disease 5)Present episode associated with allergic diseases or asthma 6)History of intake of Zinc in past three months 7)With an associated clinical diagnosis of diarrhea

Design outcomes

Primary

MeasureTime frame
i) Blood collection for zinc estimation ii)Time taken in hours for clinical resolution Timepoint: Blood collection within 24 hours

Secondary

MeasureTime frame
i)Duration of hospital stay in completed days ii)Total number of episodes of fever and cough with fast breathing (50 or more per min in 2 mo â?? 12 mo and 40 or more per min in 1 â?? 5 yrs) in next three months Timepoint: i) Duration of hospital stay from admission to discharge ii) No of episodes of pneumonia from discharge to 3 months

Countries

India

Contacts

Public ContactDr Abhijit Dutta

Assam Medical College

dr_aditib@hotmail.com9435031072

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026