Health Condition 1: null- fracture of long bones with implant.
Conditions
Interventions
Intervention1: observational study: The platelet concentrate would be obtained from patients own blood 55 ml) using the SYMPHONY platelet concentrate system. The patients with atrophic non-union with
Sponsors
Indian Council of Medical ResearchICMR
Eligibility
Inclusion criteria
Inclusion criteria: patients who has fracture of long bones (femur, tibia, humerus, radius and ulna)and atleast 6 months have passed since the time of injury and there are no clinical radiological signs of bone union. only patients with signs of atrophis non union would be included in the study.
Exclusion criteria
Exclusion criteria: 1. Patients not willing to undergo treatment. 2. patients of age more than 50 years and age less than 20 years 3. Patients with history of compound fractures. 4. Patients with previous history of metabolic disorders. 5. Patients with history of steroid intake 6. Patients with history of Endocrine disorders requiring treatment 7. Abnormal renal or liver function. 8. Patients with hypertrophic non union. 9. Patients with non union gap of more than 10 mm
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 76 patients patients were included in this study with average age was 34.5 years. 62 patients (82%) shows signs of union after platelet injection at 3 years of follow up.Timepoint: 76 patients were recruited in 3 years. evaluted after 3 years. | — |
Secondary
| Measure | Time frame |
|---|---|
| 7 fracture united out of 10 in first year. all 18 fractures unites in second year. 37 patients showed signs of union out of 48 patients in third year.Timepoint: 10 patients were included in first year. 18 patients were included in second year. 48 patients were included in third year. | — |
Countries
India
Contacts
Public ContactProf R Malhotra
All India Institute of Medical Science (AIIMS)
Outcome results
None listed