Health Condition 1: null- Late preterm and term babies with hyperbilirubinemia,otherwise healthy and breast feeding.
Conditions
Interventions
Intervention1: Higher irradiance: Higher irradiance is around 45 microwatt/cm2/nm.Baby kept under higher level of irradiance.TSB done every 12 hrly till 2 values below cutoff levels.
Control Interven
Sponsors
All India Institute Of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: • Late Preterm & Term (>=34 weeks and • Development of jaundice in 1st week with TSB levels requiring phototherapy as per AAP criteria
Exclusion criteria
Exclusion criteria: • Rh haemolytic disease • Major Congenital Anomalies • No availability of a working phototherapy unit • Refusal to consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the total duration of phototherapy (O ) in healthy late preterm and term neonates with hyperbilirubinemia during first week of life (P) treated with LED Phototherapy device , high level of irradiance (45±5µW/cm2/nm) (I) compared to low level of irradiance (22.5±5 µW/cm2/nm)Timepoint: the total duration of phototherapy till 2 serum bilirubin values are below cutoff values . | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the effect of increasing irradiance on: 1. The rate of fall of bilirubin in first 24 hours of initiating phototherapy 2. Incidence of adverse effects (hypothermia or hyperthermia ) during therapy , and 3. Proportion of infants experiencing rebound hyperbilirubinemia requiring re-institution of phototherapy within 24 hrs of its cessationTimepoint: -first 24 hrs- rate of fall of bilirubin -adverse effects during phototherapy -any rebound rise in bilirubin requiring re-phototherapy 24 hrs after stopping phototherapy | — |
Countries
India
Contacts
Public ContactDr Ramesh Agarwal
AIIMS
Outcome results
None listed