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Increase in blood glucose during surgey

Intraoperative blood glucose levels in nondiabetic patients undergoing elective major surgery under general anaesthesia receiving crystalloid solutions for maintenance fluid

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2012/09/003021
Enrollment
200
Registered
2012-09-26
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Glycemic status during intraoperative period

Interventions

Control Intervention1: 5% Dextrose: Patients in Gr B received 5% dextrose- 0.45% NaCl with 10 meq/l KCl as maintenance fluid. Fluid infusion rate will be according to the "4-2-1" rule and duration is

Sponsors

Souvik Maitra
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Nondiabetic patients of ASA physical status I or II of age group 18-60 years of either sex undergoing major noncardiac surgery (duration > 2 hours) under general anaesthesia.

Exclusion criteria

Exclusion criteria: ï?§ Unwilling patients ï?§ Patients with diabetes mellitus, impaired postprandial glucose tolerance (2h postprandial blood glucose > 126 mg/dL) and impaired fasting glucose (fasting blood glucose > 106 mg/dL) ï?§ Patients with severe respiratory, cardiovascular, neurological or renal disease ï?§ ASA physical status III and IV ï?§ Haemodynamically unstable patients ï?§ Pregnancy ï?§ Body weight ï?§ Body weight > 75 kg

Design outcomes

Primary

MeasureTime frame
Incidence of intraoperative hyperglycemia (Blood glucose 150 mg/dl)Timepoint: Blood glucose was assessed initially just before iv cannulation and again at hourly interval till the end of surgery.

Secondary

MeasureTime frame
Requirement of insulin to maintain normoglycemiaTimepoint: When we find a Blood glucose level is higher than 150 mg/dl during CBG monitoring, designated dose of Insulin was administered. Total requirement of Insulin was calculated

Countries

India

Contacts

Public ContactSouvik Maitra
palsamarendra@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026