Health Condition 1: null- Patients with Antrochoanal and Ethmodal nasal Polyps
Conditions
Interventions
Control Intervention1: 1. Risk factors
2. Gene expressions
3. Mutational analysis: 1.Risk factors will be studied in comparison to controls in the ratio of 1:1.
2. Gene expressions: Initially microar
Sponsors
Vision group on Science and techonology
Eligibility
Inclusion criteria
Inclusion criteria: 1.All cases of Antrochoanal and Ethmodial nasal polyps 2. Recurrent cases
Exclusion criteria
Exclusion criteria: 1. Immunocompromised 2. Malignancies of Nose and Paranasal sinus
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To study the risk factors responsible for occurrence of Antrochoanal(AC) and Ethmoidal (EP) nasal polyps 2.To study the difference in Gene expression Profiling of Antrochoanal and Ethmoidal nasal polyposis 3.To identify mutations if anyTimepoint: 1.Smoking, Woodstove exposure etc Time point: Jan 1st 2010 to May 30th 2012 2. Gene expression Profiling:Jan 1st 2010 to July 30th 2012 3.Mutational study: Jan 1st 2010 to July 30th 2012 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To find out the cause for recurrence 2. To find out the difference in Gene expression profiling of AC and EPs with respect to Morphological characteristics and risk factorsTimepoint: 1. Allergic rhinitis, Infection 2.Congested and Non congested polyps etc | — |
Countries
India
Contacts
Public ContactDr Vikram Bhat K
Karnataka Institute of Medical Sciences, Hubli
Outcome results
None listed