Health Condition 1: null- Prediabetes: Impaired fasting glucose (IFG) â?? Fasting Plasma Glucose 100-125 mg/dl OR Impaired glucose tolerance((IGT)- 2hr Post Prandial Glucose 140-199mg/dl
Conditions
Interventions
Intervention1: Sprint Interval Training: 60 seconds of intense exercise followed by 90 seconds of rest, repeated for 4 cycles making a total of 10 minutes a day.
Subjects using this method trained 3
Sponsors
Government Medical College Aurangabad
Eligibility
Inclusion criteria
Inclusion criteria: 1) Prediabetes: Impaired fasting glucose (IFG) â?? Fasting Plasma Glucose 100-125 mg/dl OR Impaired glucose tolerance((IGT)- 2hr Post Prandial Glucose 140-199mg/dl 2) Age group: 25 to 40 years. 3) Asymptomatic males with a normal baseline ECG
Exclusion criteria
Exclusion criteria: 1.Resting blood pressure greater than or equal to 160/100 mm Hg 2. Triglycerides greater than or equal to 500 mg/dL 3. Factors that may limit adherence to intervention or affect conduct of the trial such as lack of time, amount of travel, and/or work or family stressors 4. Unable or willing to communicate with staff, to provide written informed consent, or accept the randomized assignment 5. Failure to complete behavioral run-in and baseline testing 6. Not physically capable of performing the exercise required of the study protocols 7. Plans to be away >4 weeks in the next 6 months 8. Lack of support from primary health care provider or family members 9. Significant weight loss in the past year ( >20 kg) or current use of weight loss medications 10. Current diagnosis of schizophrenia, or other psychotic disorders, or bipolar disorder 11. History of bariatric surgery within last 3 years 12. Other temporary intervening event, such as sick spouse, bereavement, or recent move 13. Other medical, psychiatric, or behavioral limitations that in the view of the principal investigator may interfere with study participation or the ability to follow the intervention protocol 14. Underlying diseases or conditions likely to limit lifespan and/or affect the safety of the intervention 15. Self-report HIV or tuberculosis 16. History or evidence of serious arrhythmias, cardiomyopathy, congestive heart failure, aortic aneurysm, or heart transplantation 17. Renal disease: currently receiving dialysis 18. Type I diabetes mellitus 19. Type 2 diabetes mellitus, defined as: Fasting plasma glucose levels greater than or equal to 126 mg/dL 2-hour postprandial Oral Glucose Tolerance Test results greater than or equal to 200 mg/dL 20. Any other medical condition or disease that is life threatening or that can interfere with or be aggravated by exercise 21. Chronic obstructive lung disease, peripheral vascular disease or angina that limits ability to follow exercise protocol 22. Advanced neuropathy or retinopathy 23. Consuming alcoholic beverages, Smoker or have used nicotine/tobacco products within the last 12 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Insulin Resistance by Homeostatic Model Assessment (HOMA-IR)Timepoint: 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| HOMA1-IS%, HOMA-2S%, QUICKI, HOMA-1β% and HOMA-2β%, Lipid Profile, HbA1c , VO2max, Waist Hip ratio and Body Mass IndexTimepoint: 3 months | — |
Countries
India
Contacts
Public ContactDr Khaled Mohsin Badaam
Government Medical College, Aurangabad
Outcome results
None listed