Health Condition 1: null- Hyperbilirubinemia
Conditions
Interventions
Intervention1: Intermittent Phototherapy: Single surface CFL phototherapy will have a light on and off phases lasting for 2 hrs each.
Control Intervention1: Continuous Phototherapy: Single surface CFL
Sponsors
All India Institute of Medical Sciences
Dr Ashok K Deorari
Eligibility
Inclusion criteria
Inclusion criteria: Babies who were born at a gestation of >= 35 weeks and developed jaundice, with bilirubin cutoffs, requiring phototherapy within first two weeks of life, as per AAP practice parameter guidelines will be included in the study if parents are willing to give informed written consent
Exclusion criteria
Exclusion criteria: The following babies will be excluded from the study. 1. Babies with hemolytic jaundice â?? Rh, ABO, or minor group incompatibility with DCT positive or other hemolytic conditions like G6PD deficiency or peripheral smear showing hemolysis. 2. Total serum bilirubin levels 20 mg/dl 3. Sepsis (symptomatic screen positive/ culture positive) 4. Babies who have received prior phototherapy 5. Babies with hydrops fetalis or major congenital malformations. 6. Non availability of dedicated phototheraphy unit at the time of assessment for eligibility.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the rate of fall of bilirubin defined as difference between total serum bilirubin (TSB) at onset and at termination of phototherapy divided by duration of phototherapy, in continuous vs. intermittent phototherapy. Timepoint: To determine the rate of fall of bilirubin defined as difference between total serum bilirubin (TSB) at onset and at termination of phototherapy divided by duration of phototherapy, in continuous vs. intermittent phototherapy. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the efficacy of continuous vs intermittent in the management of non hemolytic hyperbilirubinemia in term and late preterm neonates in terms of 1. Duration of phototherapy (PT) in hours. 2. Failure of phototherapy and need for exchange transfusion. 3. Need for phototherapy for rebound increase in bilirubin 4. Incidence of hyperthermia 38°C 5. Maternal perception of satisfaction of care and feeding 6. Breast feeding assessment at discharge Timepoint: Ongoing monitoring till discharge | — |
Countries
India
Contacts
Public ContactDr Ashok K Deorari
All India Institute of Medical Sciences
Outcome results
None listed