Health Condition 1: null- Either sex, age between 18 to 60 years, ASA I and ASA II, posted for elective infraumbilical surgical, gynaecological, or orthopaedic operations.
Conditions
Interventions
Intervention1: Propofol: Intravenous bolus 1 mg/kg follwed by infusion 3 mg/kg/hr of propofol for sedation during spinal anaesthesia titrated to maintain BIS 65-70
Control Intervention1: Midazolam: in
Sponsors
NORTH BENGAL MEDICAL COLLEGE
Eligibility
Inclusion criteria
Inclusion criteria: Patients of either sex, of age between 18 to 60 years complying to ASA I and ASA II criteria, who are posted for elective infraumbilical operations (be it surgical, gynaecological, or orthopaedic), of approximate 90 mins duration.
Exclusion criteria
Exclusion criteria: a. Patient not willing to accept spinal anaesthesia b. Patient not willing to receive sedation during surgery under spinal anaesthesia c. Patient not willing to participate in the study d. Patient having any of the followingâ?? Neurological Disease Local infection at the site of inducing the block Spinal deformity, past history of spine surgery or trauma Coagulopathy Psychiatric Illness Any history of allergy to the drugs to be used for the study Any significant cardiovascular and pulmonary disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| arousal time from sedation following stoppage of infusionTimepoint: arousal time from sedation following stoppage of infusion | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.time of onset of sedation 2.intraoperative haemodynamic changes 3.patientsâ?? satisfaction regarding quality of intraoperative sedation 4.adverse events if any. Timepoint: 1.time to onset of sedation:from start of infusion of study drug to the desired level of sedation 2.intraoperative haemodynamic changes: with respect to changes in Mean Arterial Pressure (MAP)in mm of Hg and the changes in heart rate (bpm)at 10 min interval 3.patients satisfaction: at the point of recovery 4.adverse events: intraoperative | — |
Countries
India
Contacts
Public ContactDIPANJAN BAGCHI
Department of Anaesthesiology, North Bengal Medical College
Outcome results
None listed