Health Condition 1: null- neonates of either sex admitted in NICU, in whom a longline insertion is indicated for therapeutic reasons
Conditions
Interventions
Intervention1: heparin infusion in long lines: Heparin 0.5IU/ml of TPN solution
Control Intervention1: no heparin infusion in neonatal loglines: no Heparin infusion
Sponsors
Department of Pharmacology IPGMER Kolkata
Eligibility
Inclusion criteria
Inclusion criteria: Neonates of either sex admitted in the NICU in whom a longline insertion is therapeutically indicated. Parents of the neonates should provide written informed consent
Exclusion criteria
Exclusion criteria: Neonates in whom the blood culture report or septic screen is positive prior to insertion of longline Neonates in whom the blood culture becomes positive within 48 hours of insertion of the longline
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of episodes of catheter related blood stream infectionTimepoint: Number of episodes of catheter related blood stream infection | — |
Secondary
| Measure | Time frame |
|---|---|
| ï?§ Number of bacteraemic episodes with organisms not commonly associated with line sepsis such as gram negative bacilli where the pathogenesis is not likely to be inhibited by heparin and microthrombi in the catheter tip is not expected to be a major nidus of infectionTimepoint: Number of episodes of catheter related blood stream infection | — |
Countries
India
Contacts
Public ContactDr Suparna Chatterjee
Associate Professor, Dept of Pharmacology, IPGMER, Kolkata
Outcome results
None listed