None listed
Conditions
Interventions
Intervention1: Passive case detection (PCD) and Intermittent screening and treatment (IST): In PCD Group,pregnant women with 18-28 weeks of gestation will be enrolled. Enrolled women with pregnancy h
if malaria positive treatment will be given as per National Policy.
In IST group Pregnant women with 18-28 weeks gestation will be enrolled. Rapid Diagnostic Tests will be performed in all women ir
Sponsors
Malaria in Pregnancy Consortium Liverpool
Eligibility
Inclusion criteria
Inclusion criteria: (1)Pregnant women of all parities will be eligible. (2)Women having a gestational age between 18 and 28 weeks at first contact will be eligible
Exclusion criteria
Exclusion criteria: (1)Women having a gestational age >28 weeks at first contact will be excluded (2)Women having a gestational age (3)Women having a chronic disease (cardiac, renal, hepatic) will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Placental malaria (histological or PCR confirmed past, acute and/or chronic; or placental blood smear or RDT positive for malaria) Timepoint: 6 months after birth outcome | — |
Secondary
| Measure | Time frame |
|---|---|
| (1)Clinical malaria defined a (History of fever within 48 hours or measured Temp 37.5°C) + ( RDT positive or parasitaemia of any density) (2)Maternal Moderate-severe anaemia (Hb 9 gm/dl) (3)Low birth weight (2500gm). (4)Birth outcomes(abortion, still birth, nearly neonatal death, and prematurity) (5)Rate of exposure to malaria (AMA1 sero-conversion) (6)Sensitivity and specificity of RDTs to detect MiP Timepoint: 6 months | — |
Countries
India
Contacts
Public ContactDr Neelima Mishra
National Institute of Malaria Research
Outcome results
None listed