Health Condition 1: null- Adult patients of ASA grade 1 and 2 status undergoing lobectomy or pneumonectomy by open technique
Conditions
Interventions
Intervention1: post-operative spirometry and DLCO: post-operative spirometry and DLCO
Control Intervention1: Not applicable: Not applicable
Sponsors
Tata Memorial Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients of ASA grade 1 and 2 status undergoing pulmonary lobectomy or pneumonectomy by open technique
Exclusion criteria
Exclusion criteria: • Patients undergoing non-anatomical lung resections like wedge resections or metastatectomies • Patients who have received neoadjuvant radiotherapy to the lung • Unreliable for medium term follow-up • Patients with permanent tracheostomies • Patients with oro-facial anomalies (unable to perform spirometry) • Lower limb amputations / abnormalities (e.g. arthritis) - unable to perform 6 minute walk test • Thoracoscopic resections • Patients undergoing repeat surgeries of the thorax or lower limb before the 3 month follow up (e.g. re-exploration, metastatectomy)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Correlation and agreement between calculated and actual post-operative) values of a. post-operative FEV1 % b. post-operative DLCO % Timepoint: 2 to 4 days, 10 to 14 days and 4 to 6 months after lung resection | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Association between adjuvant therapy and change in FEV1, DLCO and functional capacity 2. Association between (ever) smoking and change in FEV1, DLCO and functional capacity Timepoint: 4 to 6 months post-operative;1. Change in functional capacity (6MWT parameters) before and after resection: i. Distance covered during 6MWT ii. Desaturation during the test (fall in oxygen saturation by more than four percent from baseline or below 86%) Timepoint: 4 to 6 month post-operative;1. Correlation and agreement between calculated and actual post-operative) values of a. post-operative FEV1 % b. post-operative DLCO % Timepoint: 2 to 4 days post-operative, 10 to14 days post-operative | — |
Countries
India
Contacts
Public ContactPriya Ranganathan
Tata Memorial Hospital
Outcome results
None listed