Health Condition 1: null- Preterm infants between 26-32 weeks gestation requiring continuous positive airway pressure
Conditions
Interventions
Intervention1: Nasal mask: Application of continuous positive airway pressure (CPAP) through nasal CPAP masks available in 3 sizes. This is to be given continuously till the baby has respiratory distr
Sponsors
All India Institute of medical sciences
Eligibility
Inclusion criteria
Inclusion criteria: Preterm babies of 26+0 â?? 32+6 weeks of gestation Respiratory distress requiring CPAP within 6 hours of life Informed parental consent
Exclusion criteria
Exclusion criteria: Major congenital malformations Any known anomaly known to interfere with delivery of CPAP such as congenital diaphragmatic hernia, trachea oesophageal fistula, choanal atresia, cleft palate and nasal deformities, severe cardiovascular instability.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Area under the curve of FiO2 against time during the first 72 hours of CPAP application 2. Mean FiO2 requirement at 24 , 48 and 72 hours of CPAPTimepoint: 1. Area under the curve of FiO2 against time during the first 72 hours of CPAP application 2. Mean FiO2 requirement at 24 , 48 and 72 hours of CPAP | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Proportion of babies requiring intubation in the first 72 hours of life 2. Proportion of babies who develop nasal trauma 3. Physiological variables including the mean respiratory rates and heart rates as well as Silvermanâ??s score during the first 72 hours 4. Incidence of oxygen dependency at 28 days postnatal life, air leaks Timepoint: Physiological variables are measured at baseline and at 1, 2, 6, 12, 18, 24 hours and every 6th hourly thereafter until 72 hours of CPAP. Nasal trauma will be graded by an independent observer daily during first 72 hours till CPAP is removed | — |
Countries
India
Contacts
Public ContactAparna Chandrasekaran
All India Institute of Medical sciences, New Delhi
Outcome results
None listed