Health Condition 1: null- metabolic syndrome
Conditions
Interventions
Intervention1: Vit D: 60000 IU weekly for 8 weeks followed by monthly for 4 months
Control Intervention1: Placebo of vit D granules: 1 gm PO, weekly for 8 weeks followed by 1 gm , monthly for 4 months
Sponsors
St Johns Research Institute
Eligibility
Inclusion criteria
Inclusion criteria: Assessment for inclusion in the study Individuals will be included in the study if they satisfy all of the following conditions: i) Age 35 to 65 years ii) Waist circumference of 90cm or more in men, and 80cm or more in women iii) Any two of the following four factors: • raised TG level: > 150 mg/d, or specific treatment for this lipid abnormality • reduced HDL cholesterol: • raised blood pressure: systolic BP 130 or diastolic BP 85 mm Hg, or treatment of previously diagnosed hypertension • fasting plasma glucose (FPG) 100 mg/dL (5.6 mmol/L)
Exclusion criteria
Exclusion criteria: 1. Known diabetes or pre-diabetes defined as a Fasting Blood Sugar >110 mg/dl. 2. Receiving/received Vitamin D or calcium supplementation in the previous 3 months 3. History of Chronic disease-renal/ hepatic/ malignancy /gastrointestinal ( Mal absorption syndromes ) 4. Patients who have received Anticonvulsants, glucocorticoids or ART medication in the past one month 5. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of insulin resistance calculated by HOMA IR at the end of 6 monthsTimepoint: Reduction of insulin resistance calculated by HOMA IR at month 6 | — |
Secondary
| Measure | Time frame |
|---|---|
| NATimepoint: NA | — |
Countries
India
Contacts
Public ContactDr Saba Fathima
St Johns Research Institute
Outcome results
None listed