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A clinical trial to study the effect of the drug methylprednisolone injection when given at 2 different sites, in patients with Carpal Tunnel Syndrome

Comparison of efficacy of local corticosteroid injection into carpal tunnel:Distal Vs Proximal approaches in patients with carpal tunnel syndrome

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2012/07/002813
Enrollment
218
Registered
2012-07-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Carpal Tunnel Syndrome

Interventions

Intervention1: Methyl prednisolone 40mg/ml: Each participant will be randomized to receive active intervention at one of the sites ie.either proximal or distal.If in a patient randomization is coming

Sponsors

JIPMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients coming to Neurology OPD with symptoms & signs of CTS of atleast 3 months with atleast one of the following electrophysiology features Median motor distal Latency >4.5 ms Difference in Median and Ulnar motor distal latency >0.5ms Median sensory latency >3.4ms Difference in Median and Ulnar sensory peak Latency >0.5ms

Exclusion criteria

Exclusion criteria: Severe CTS with thenar atrophy 18 years of age Not willing to participate/give consent Contraindications for corticosteroid injections (eg: skin infection at site) Traumatic/Neoplastic origin of symptoms

Design outcomes

Primary

MeasureTime frame
The CTS symptom severity score (SSS)change at 1 month after treatment. Timepoint: The CTS symptom severity score (SSS)change at 1 month after treatment.

Secondary

MeasureTime frame
The CTS SSS changes at 3 month Direct treatment response at 1 month(physician) Improvement as perceived by patient Proportion of patients referred for surgery Adverse events Time taken for the procedure Pain perceived during the procedure Timepoint: at the time of procedure 2 weeks,1 month,3 months after injection

Countries

India

Contacts

Public ContactDrPradeep P Nair

Jawaharlal Institute of Post graduate Medical Education and Research

drpradeeppnair@rediffmail.com09489146560

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026