Role of leptin in Polycystic ovarian syndrome and effect of metformin therapy on its levels.

Estimation of Serum Leptin levels and its correlation with various indices of Polycystic Ovary Syndrome and effect of Metformin on Leptin levels in Polycystic Ovary Syndrome patients.

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2012/07/002806

Enrollment

Registered

2012-07-16

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Polycystic ovary syndrome

Interventions

Intervention1: Metformin: Tablet Metformin 750 mg orally two times a day for 3 months Control Intervention1: No treatment: -

Eligibility

Inclusion criteria

Inclusion criteria: For Group 1- Newly diagnosed PCOS For group 2- Normally cycling BMI matched

Exclusion criteria

Exclusion criteria: For Group 1- Any other known cause of amenorrhea Taking concomitant medication for PCOS Known hypersensitivity to Metformin Chronic heart, pulmonary, kidney, liver disease Uncontrolled diabetes with possibility of DKA For Group 2- Any chronic systemic illness

Design outcomes

Primary

Measure	Time frame
a) To compare Leptin concentration in PCOS patients with BMI controlled normally cycling healthy women. b) To correlate serum Leptin level with clinical and biochemical indicators of PCOS patients Timepoint: 3 months	—

Secondary

Measure	Time frame
To evaluate effect of Metformin on Leptin level in PCOS patients.Timepoint: 3 months	—

Countries

India

Contacts

Public ContactDr Sunita J Ramanand

Government Medical College, Miraj

pharmac.ctri@gmail.com09850547900

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026