FindTrial
Sign In

The use of intravenous dexmedetomidine as an additional drug to epidural morphine in providing adequate pain relief and sedation in patients undergoing major operations like thoracotomy.

Effect of intravenous dexmedetomidine as an adjuvant to epidural morphine on the perioperative analgesic requirement in patients undergoing thoracotomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2012/06/002746
Enrollment
30
Registered
2012-06-26
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- carcinoma lung patients undregoing thoracotomy

Interventions

Intervention1: Dexmedetomidine: Initial bolus - 1 microg/kg over 10 min, followed by 0.4 microg/kg/hr infusion till end of surgery. Control Intervention1: normal saline: Initial bolus of 1 ml/kg/min

Sponsors

ALL INDIA INSTITUTE OF MEDICAL SCIENCES
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ELECTIVE THORACOTOMY

Exclusion criteria

Exclusion criteria: • patients refusal to participate • patients who have psychiatric disturbances • severe chest wall/spinal deformity • patients with coagulation disorders/pts on anticoagulants • severe ventricular dysfunction • patients in shock • liver disease patients

Design outcomes

Primary

MeasureTime frame
To study the effect of intravenous dexmedetomidine as an adjuvant to epidural morphine on perioperative analgesic requirement in patients undergoing thoracotomy. Timepoint: Amount of intravenous morphine used intaraoperatively in each groups—

Secondary

MeasureTime frame
Postoperative analgesia requirementTimepoint: Total amount of PCA morphine used at the end of 24 hrs in postoperative period—

Countries

India

Contacts

Public ContactLOKESH KASHYAP

AIIMS

lokeshkashyap@yahoo.com9868397821

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026