FindTrial
Sign In

use of mifepristone for induction of labor in women with previous one low segment cesarean section comparison with mechanical stretching of cervix

INDUCTION OF LABOR IN WOMEN WITH PREVIOUS ONE CESAREAN SECTION: PROSPECTIVE DOUBLE BLIND RANDOMIZED CONTROL TRIAL COMPARING THE EFFECT OF MIFEPRISTONE WITH SWEEPING STRETCHING AND TRANS-CERVICAL FOLLEYâ??S CATHETERIZATION

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2012/06/002733
Enrollment
200
Registered
2012-06-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- pregnant patients 40 weeks gestation with single cephalic pregnancy & previous one low segment cesarean section

Interventions

Intervention1: drug mifepristone compared with mechanical stretching of cervix by sweeping stretching & trans-cervical folleys catheter: Group 1 Women in this group will have initial assessment of bis

Sponsors

DR RAJENDRA PRASAD GOVERNMENT MEDICAL COLLEGE KANGRA AT TANDA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • Singleton pregnancy • Previous one low segment cesarean section, no other uterine scar or previous rupture • Gestation beyond 40 weeks • Cephalic presentation

Exclusion criteria

Exclusion criteria: • Inter-conceptional period less than 18 months • Estimated fetal birth weight > 4kg • Poor modified bio-physical profile (Amniotic fluid index • Poor dating ( not sure of dates, no ultrasonography in first trimester or two serial ultrasounds 4 weeks apart in second trimester) • Premature rupture of membranes/ chorio-amniotis • Premature rupture of membranes/ chorio-amniotis • Evidence of fetal distress at admission • Intra-uterine fetal death • Any maternal disease ie hypertension, diabetes, renal disease, liver disease, cardiac disease, epilepsy or any chronic medication • Any contraindication for vaginal delivery ( cephalo-pelvic disproportion ruled out) • Type of caesarean section not known ( classical or low segment)

Design outcomes

Primary

MeasureTime frame
To compare the proportion of women entering labor after use of mifepristone alone as compared to sweeping stretching of cervix or use of trans-cervical folleyâ??s catheter.Timepoint: 48 hours after intervention & subsequently delivery of fetus—

Secondary

MeasureTime frame
â?¢ Proportion of women vaginally delivered in each group â?¢ Proportion of women with cesarean section in each group â?¢ Duration of labor in women in each group â?¢ Need and amount of oxytocin required in each group â?¢ Proportion of women with scar dehiscence/ rupture in each group â?¢ Neonatal outcomes â?? Timepoint: 48 hours—

Countries

India

Contacts

Public ContactChanderdeep Sharma

DR RPGMC KANGRA (HP)

sureshsverma@gmail.com91-9218925471

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026