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A study to see the effect of gabapentin in pain management after operation

Effect of pre-operative Gabapentin on early post operative pain, nausea, vomiting and analgesic consumption following Hysterectomy in AGMC & GBP Hospital

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2012/05/002700
Enrollment
60
Registered
2012-05-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients Undergoing elective hysterectomy under spinal anesthesia

Interventions

Intervention1: Gabapentin: One Capsule 300mg once, one hour before Spinal Anesthesia Control Intervention1: Placebo: One Capsule one hour before spinal anesthesia

Sponsors

Indian Council of Medical Research
Lead Sponsor
Agartala Govt Medical College
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: a. 18 yrs or older. b. Patient with American Society of Anesthesiologists (ASA) classification grade I & Grade II will be included. c. Undergoing elective hysterectomy under spinal anesthesia.

Exclusion criteria

Exclusion criteria: a. Patients with present history of pregnancy. b. Patients with history of epilepsy or chronic pain, or use of anti epileptic drugs or neuropathic analgesics. c. Patient with American Society of Anesthesiologists (ASA) classification of III or greater. d. Patients with a history of opioid or intravenous drug abuse. e. Patients with known allergy to gabapenin. f. Patients who have taken antacid medication in the previous 24 hrs. g. Patients who refused Spinal anaesthesia.

Design outcomes

Primary

MeasureTime frame
pain score by Visual analogue scale (VAS)Timepoint: At 4hr 24 hour and 48 hour post operatively

Secondary

MeasureTime frame
1. Post Operative Nausea Vomitting, drowsiness, & pruritus. 2. Total dose of analgesic consumption. 3.Time of 1st request of the patient for analgesics. Timepoint: At 4hr 24 hour and 48 hour post operatively

Countries

India

Contacts

Public ContactDr Debasis Ray

Agartala Govt Medical College

contactdebasisray@gmail.com09436125100

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026