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Treatment of infertility by intrauterine insemination

Evaluation of role of GnRH antagonists in intrauterine insemination cycles(IUI) with mild ovarian hyperstimulation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2012/05/002682
Enrollment
60
Registered
2012-05-22
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: cetrorelix acetate injection: GnRH antagonist- cetrorelix acetate 0.25mg subcutaneous will be administerd in study group when follicle size is 16 mm and will be given till follicle rea

Sponsors

Employee state insurance post graduate institute of medicine and researchBASAIDARAPUR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 2. Primary or Secondary infertility 3. BMI â?? 18 â?? 30 kg/ m2 4. Regular menstrual cycles (25-35 days) 5. Normal basal FSH( 6. Patients with unexplained infertility 7. Mild male factor 8. Patency of both or either one of the tubes (HSG/Laprohysteroscopy).

Exclusion criteria

Exclusion criteria: 2. Antral follicle count 4 3. Patients with uterine anomalies. 4. Patients with PCOS (as per Rotterdam criteria) 5. Patients with endometriosis.

Design outcomes

Primary

MeasureTime frame
1. LH surge and premature lutenisation ( S.LH 20 mIU/ml, S.Prog 1ng/ml)13 2. Pregnancy rate Timepoint: 1. LH surge and premature lutenisation ( S.LH 20 mIU/ml, S.Prog 1ng/ml)13 2. Pregnancy rate

Secondary

MeasureTime frame
1. Number of oocytes 18mm on day of trigger 2. Estradiol levels on the day of trigger 3. Duration of use of GnRH antagonist 4. Amount of gonadotropins used 5. Incidence and severity of OHSS 6. Impact of GnRH antagonists on endometrial thickness. 7. Total duration of therapy Timepoint: one month

Countries

India

Contacts

Public ContactDr Leena Wadhwa

Employee state insurance- post graduate institute if medicine and research,Basaidarapur,Delhi

khannarupali@hotmail.com8447588017

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026