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Starch acetate in treatment of diarrhoea

Esterified starch and oral rehydration solution as a treatment for acute infectious diarrhoea - ES-ORS

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2012/05/002680
Enrollment
100
Registered
2012-05-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Acute gastroenteritis with dehydration

Interventions

Intervention1: High amylose maize starch acetate: 10g along with each 200 ml ORS as per WHO Plan B, until diarrhoea stops or 72 hours Control Intervention1: High amylose maize starch: 10g along with e

Sponsors

Christian Medical College
Lead Sponsor
Department of Biotechnology
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Acute watery diarrhoea of less than three days duration with dehydration.

Exclusion criteria

Exclusion criteria: Bloody diarrhoea Concomitant illness: In adults this includes malignancy, sepsis, and a history of coronary artery disease or stroke.

Design outcomes

Primary

MeasureTime frame
Duration of diarrhoeaTimepoint: Time from commencing therapy to the first formed stool or to the end of a 12 hour period without any stool.;Duration of diarrhoeaTimepoint: Time from commencing therapy to the first formed stool or to the end of a 12 hour period without any stool.;Duration of diarrhoeaTimepoint: Time from commencing therapy to the first formed stool or to the end of a 12 hour period without any stool.

Secondary

MeasureTime frame
Stool frequency Need for unscheduled intravenous fluids Proportion of patients who recover from diarrhoea at 24 hours and at 48 hours Timepoint: 24 hours and 48 hours

Countries

India

Contacts

Public ContactBS Ramakrishna

Christian Medical College

rama@cmcvellore.ac.in04162282052

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026