Health Condition 1: null- patients of cholelithasis who will undergo laproscopic cholecystectomy
Conditions
Interventions
Intervention1: different low doses of clonidine and normal saline: we will compare the efficacy of different low doses of clonidine and normal saline
Group 1)- Normal Saline
Group 2)- clonidine 0.5
Sponsors
Subharti Medical College Meerut
Eligibility
Inclusion criteria
Inclusion criteria: ASA grade 1 and 2 undergoing laproscopic cholecystectomy
Exclusion criteria
Exclusion criteria: Morbid obese hypertension Renal,Caddiac, cerebrovascular, Hepatic diseases and endocrine dysfunction Alcohol/ Drug abuse Patients taking antidepressatns/ antihypertensives/ antiepileptic drugs Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| to find the efficacy of different low doses intravenous clonidine on hemodynamic stability during intubation,pneumoperitoneum and extubationTimepoint: Preoperatively ,after study drug ,1 min after induction,1 min & 5 min after intubation,before pneumoperitoneum ,at 5,10,20,30,40min after pneumoperitonium ,just after extubation ,post operatively at 15 and 30 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| 1).To study the efficacy of low dose clonidine on anesthesia requirement and recovery profile 2). To compare the efficacy of different doses of clonidine on hemodynamic stability, anesthesia requirement and recovery profileTimepoint: 1)time to extubation 2)recovery time- time to response to verbal commands(spontaneous eye opening)and orintation time( to recollect name, date of birth and location) | — |
Countries
India
Contacts
Public ContactDr Ruchi Choudhary
Subharti Medical College, Meerut
Outcome results
None listed