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Comparison of demedetomidine and buprenorphine added to bupivacaine in spinal anesthesia for caesarean section

A comparison of dexmedetomidine and buprenorphine as adjuvants to intrathecal bupivacaine for postoperative analgesia for caesarean section

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2012/05/002625
Enrollment
90
Registered
2012-05-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Pregnant patients undergoing elective caesarean section

Interventions

Intervention1: Dexmedetomidine: 10 mcg added to 1.8 ml of bupivacaine 0.5 % heavy Control Intervention1: Buprenorphine: 60 mcg added to 1.8 ml of bupivacaine 0.5 % heavy Control Intervention2: Control

Sponsors

Department of Anesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Full-term parturient requiring lower segment Caesarean section under spinal anesthesia 2) ASA class I or II

Exclusion criteria

Exclusion criteria: 1) Contraindication to neuraxial blocks 2) Major systemic disease(ASA grades III or more) 3) Known allergy to any of the study drugs

Design outcomes

Primary

MeasureTime frame
Dexmedetomidine is more effective for post operative analgesia Buprenorphine is more effective for postoperative analgesia Timepoint: intraoperative period, postoperative period—

Secondary

MeasureTime frame
adverse effectsTimepoint: intraoperative period, postoperative period—

Countries

India

Contacts

Public ContactDr Sidhesh Bharne

Goa Medical College

shirley_dsouza05@yahoo.com9822159170

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026