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Appropriate dose of Vitamin-D for treatment of Vitamin-D deficiency

Appropriate dose of Vitamin-D (3L IU or 6L IU) for treatment of vitamin-D deficiency in small children: A double blind randomised trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2012/05/002621
Enrollment
56
Registered
2012-05-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Children found to have vitamin-D deficiency

Interventions

Intervention1: Vitamin D 3L IU oral stat(only once): Intervention group will recieve 3L IU vitamin D oral stat(only once) Control Intervention1: Vitamin D 6L IU oral stat (only once): Comparator group

Sponsors

ICMR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 25(OH)D levels below 20 ng/ml

Exclusion criteria

Exclusion criteria: 1. Children with chronic liver or kidney disease 2. Children with congenital malformations 3. Children on long term anticonvulsants, diuretics or steroids for more than 1 months 4. Known hypersenstivity to vitamin-D

Design outcomes

Primary

MeasureTime frame
Proportion of children with hypervitaminosis(Increased urine Ca and Cr ratio and or S.Ca more than 13 mg%) at 7-10 days after therapyTimepoint: Proportion of children with hypervitaminosis(Increased urine Ca and Cr ratio and or S.Ca more than 13 mg%) at 7-10 days after therapy

Secondary

MeasureTime frame
1. Proportion of children with hypercalciuria(Increased urine calcium and creatinine ratio) 2. Proportion of children with hypervitaminosis (Increased urine calcium creatinine ratio and or S.calcium more than 13 mg%) 3. Proportion of children with sufficient serum 25(OH)D levels (20-100 ng/ml)Timepoint: 1. at 3-5 days after therapy 2. at 25-30 days after therapy 3. at 25-30 days after therapy

Countries

India

Contacts

Public ContactDR SANJAY VERMA

PGIMER, Chandigarh

drjiyalal49@gmail.com91-887282644

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 12, 2026