Health Condition 1: null- Eclampsia during pregnancy and postpartum period
Conditions
Interventions
Intervention1: MAGNESIUM SULPHATE - STUDY GROUP: Loading dose:
Magnesium sulphate (3 g) slow IV injection over a period of not less than 5 minute, preferably 10 minute. Magnesium sulphate (50%) 6ml di
Sponsors
NIL
Eligibility
Inclusion criteria
Inclusion criteria: All cases of eclampsia â?? antepartum, intrapartum, postpartum with following diagnostic criteria: a) Hypertension where BP 140/90 mm Hg or more b) Proteinuria (more than 0.3g/L or more than + 1) c) Convulsion occurring at gestational age > 20 weeks, or within 48 h of delivery
Exclusion criteria
Exclusion criteria: Eclampsia with the following conditions will be excluded: a. Renal failure b. Deeply comatosed c. Hypotensive patient d. Clinical or imaging evidence suggestive of intracranial haemorrhage e. Diagnosis is doubtful f. Patients who had other causes of convulsions such as epilepsy, meningitis, trauma, and cerebral malaria etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The outcomes of two regimens are compared in terms of a) Rate of recurrent convulsions b) Maternal mortalityTimepoint: Till discharge | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Magnesium Sulphate â?? a)Total amount of magnesium sulphate received by each patient with or without maintenance dose b) Total no. of maintenance dose received c) Total no. of additional dose of magnesium sulphate received d) clinical evidence of magnesium toxicity such as absent patellar jerk, respiratory depression to be found 2. Mode of delivery Normal delivery/ caesarean section/ forceps 3. Maternal morbidity 4. Perinatal mortality 5.Neonatal morbidityTimepoint: Till discharge | — |
Countries
India
Contacts
Public ContactProfessor Narayan Jana
Burdwan Medical College
Outcome results
None listed