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comparison of two drugs which lowers proteinuria in diabetic kidney disease

A comparative study of antiproteinuric effect of Ramipril versus Telmisartan in Diabetic nephropathy with concomitant hypertension in a tertiary care hospital.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2012/04/002550
Enrollment
100
Registered
2012-04-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Diabetic Nephropathy with concomitant Hypertension

Interventions

Intervention1: Angiotensin Converting Enzyme Inhibitor - RAMIPRIL : RAMIPRIL 5mg orally OD for 3 months Control Intervention1: Angiotensin Receptor Blocker - TELMISARTAN: TELMISARTAN 40mg orally OD fo

Sponsors

Sowmya Bondalapati
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • All IP/OP diagnosed with Type II DM with concomitant mild to moderate hypertension associated with albuminuria detected by dip stick method. • DN patients either on Insulin / Oral hypoglycemics.

Exclusion criteria

Exclusion criteria: • Age 30 and 65 years of either sex • Patients diagnosed with Type I DM/ IDDM • Patients with severe hypertension. • Patients with proteinuria who are on dialysis/ renal transplant • Patients with H/O concomitant illness: TB/ CHF/ BA/ Epilepsy/ Ascites. • Pregnant / lactating women • Patients with H/O of other causes of proteinuria like analgesic nephropathy, nephrolithiasis, renal malignancies, metastasis to kidney, UTI, SLE, PKD.

Design outcomes

Primary

MeasureTime frame
Reduction in Urine ALBUMINTimepoint: Baseline visit, 4 weeks, 8 weeks, 12 weeks.

Secondary

MeasureTime frame
Reduction in spot PCR and Glycosylated Hb levelsTimepoint: Baseline visit, 4 weeks, 8 weeks, 12 weeks.

Countries

India

Contacts

Public ContactSowmya Bondalapati

MAMATA MEDICAL COLLEGE and HOSPITAL affiliated to NTR University of Health Sciences

vdrao1@rediffmail.com9849093421

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026